Treatment

There are no specific, effective drug treatments for the lack of coordination seen with ataxia symptoms. Amantadine and buspirone hydrochloride (BuSpar) are often tried with variable success. For episodic ataxia, acetazolamide (Diamox) can be effective. Clonazepam (Klonopin) is effective in treating specific symptoms, such as muscle jerking (myoclonus) and sleep disturbances.

Depression is common in patients with cerebellar ataxia. This is understandable in terms of the disability resulting from the condition. Recent research also indicates that patients with cerebellar ataxia may be prone to depression because of dysfunction of the cerebellum.  This, however, has not yet been proven.  Medication and emotional support are usually effective in treatment of depression in cerebellar ataxia.  

Physical therapy, such as conditioning and strengthening exercise, is also important. People who are not overweight, well conditioned, and flexible cope better with ataxia symptoms. Physical therapy can also help people use mobile aids more effectively and feel safer at home.

(For more information about specific treatments for the different types of ataxia, see Types of Ataxia.)